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Necora puber. Photograph: Hans Hillewaert

Cancer is one our most feared diseases, so it isn’t surprising that we notice when it is linked to other parts of our lives. And it’s also not surprising that stories which sound plausible, but which may or may not be supported by evidence, or which are misunderstood, become part of our culture. Three such stories are, that we are in an epidemic of cancer, that vitamin C is a useful anti-cancer agent, and that an abortion increases a woman’s risk of later breast cancer.… Read the rest “Three Cancer Myths”

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Samuel Hahnemann, father of homeopathic medicine.

A paper published in the June 30, 1988 issue of the high-profile scientific journal Nature shocked the biomedical research world. Its anodyne title, “Human Basophil Degranulation Triggered by Very Dilute Antiserum Against IgE”, probably didn’t cause any non-scientists to choke on their breakfast cereal. But in the eyes of the mainstream scientific world, the article made a radical claim: Pure water, admittedly with a special history, could generate an immune reaction in a test tube.… Read the rest “The Fading Memory of Water”

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In April 2017 I published a post titled “Why is there so much talk about Epigenetics?”. I think I did a pretty decent job explaining what Epigenetics is, and why it is such a critically important part of biology. The gist is, that the regulated output of our genomic information depends on Epigenetics. This is achieved by specific chemical groups and protein along the chromosomes that control their expression into the proteins and other products needed for the life of a particular cell.… Read the rest “Why there is so much talk about epigenetics”

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Peter Nowell and David Hungerford in 1960

 

Chronic Myeloid Leukemia (CML) is not a cancer you hear about very often. That’s not because it isn’t serious — until recently, it carried a frightening prognoses. Until about 2000, newly diagnosed CML patients had a 5-year survival rate of 31%. But we don’t hear much about CML because it is a rare disease, and affects far fewer people than cancers of the breast or prostate, or lung cancer.Read the rest “Chronic Myeloid Leukemia: a Molecular Diagnosis”

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Dr. Brian Druker and Ms. LaDonna Lopossa, one of the earliest patients to benefit from Gleevec

Rob Schick is the Branch Manger of the Baird Wealth Management Group in Portland, Oregon. Most people would probably consider him lucky. For starters, Portland is one of the most desirable cities in the United States to live in. He and his wife have three grown children, one of whom works at the same company. In addition to his success in business, Rob Schick’s efforts on behalf of the Knight Cancer Institute, where he has helped raise millions of dollars for research, were nationally recognized in 2015 by a National Community Service Award from the Invest in Others Foundation.Read the rest “Chronic Myeloid Leukemia: A Molecular Solution”

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“I think the notion of ‘calories in vs. calories out’ is ridiculous.” So begins a recent online article about diet. Typically, it cites no external sources of information for this opinion. Actually, the calories in – calories out equation is a truism; thermodynamics doesn’t make exceptions, and one way or another, those input calories have to go somewhere. But the thought underlying the denial of equivalence is usually something different, such as, why does my friend eat anything she likes and stay slim, when I can’t?Read the rest “Calories in equals calories out?”

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The present-day Gila River in the Gila Box Riparian National Conservation Area in southeast Arizona. 

Both nature and nurture affect human obesity. For some people, and for some populations, the genetic tendency to become obese is not fulfilled because of their environment, the circumstances of their lives. But when those circumstances change, the genetic potential may be realised quickly, and lead to the medical issues that follow from obesity. An example that starkly illustrates this comes from the sunbaked desert south of Phoenix, Arizona.Read the rest “The Gila River People, Victims of Modernity”

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Jesse Owens starting the 200 meter race at the 1936 Olympics. Reproduction of photograph in “Die Olympischen Spiele, 1936” p.27, 1936. 

Coverage of the recent victory of the New Zealand team in the America’s Cup yacht race featured sailboats flying along on their underwater foils at ridiculous speed, speeds reaching more than 50 miles (80 km) per hour. Whether it’s running, or driving a car, or sailing these mutant boats, speed is exciting.Read the rest “Speed Limits”

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There’s a great new book about vitamin A, “Brilliance & Confusion: Saving Children’s Vision & Lives With Vitamin A”. Okay, I confess. It’s my own book, which I’ve just published. Vitamin A was discovered in 1913, but it has continued to provide surprises since. The most important of these is that it isn’t essential just for vision, which is what most people know about it. Rather, it is needed to maintain many functions necessary for health, and life itself.Read the rest “A Great New Book”