One of the most tantalizing aspects of cancer biology is this: that the normal immune system often recognizes growing tumors, and even targets them for destruction, but then is silenced. This story is about how to wake it up and mobilize it to greater anti-tumor activity. It is a story that reaches back a hundred years, to the innovative work of an esteemed German biochemist. It was his conviction that he had identified a key feature of cancer that would provide an opening for its treatment.… Read the rest “Cancer Therapy: Old is New Again”